Menstrual Losses. Dr Julius Heitzmann reports the employment of Pepto-Mangan with much success in chlorosis and in cases of anaemia in girls and women due to loss of blood, menorrhagia, inflammation of the pelvic organs, peri-and parametritis or prolonged leucorrhea. He says: "In almost every instance I observed within a short time increase of appetite, improved nutrition, healthier color of the face and increase of weight. I was surprised to learn how much more readily the Pepto-Mangan was taken than similar preparations, without ill-effects even after protracted use."-Allgem. Wiener Med. Zeitung. (From Medic. Chirurg. Central Blatt.) Dr. Otto Roen says that all the chalybeates hitherto in use do not satisfy the chief requirement, namely, a neutral reaction, and lack one important factor so necessary in the treatment of chlorosis and anaemia, namely manganese. In Pepto-Mangan (Gude) it has been found possible to unite all the advantages and eliminate all the disadvantages of ferruginous preparations. As seen from the published literature-which he reviews-clinical experiments extending over ten years have proved it the iron preparation par excellence, the only one in which manganese plays a prominent part as an oxygen carrier to the blood.